| Research Tools | Not rated | 10,062 | $92,500 |
| Quantitative Research | Maintain | 7,832 | $137,500 |
| Research Computing | Invest | 762 | $152,500 |
| Research Data Management | Invest | 543 | $67,500 |
| FlowJo | Maintain | 259 | $97,500 |
| NVivo | Maintain | 223 | $77,500 |
| Reproducible Computational Environment Engineering | Invest | 139 | $142,500 |
| Inverse Problems | Maintain | 114 | $137,500 |
| Waters Empower 2 | Migrate | 100 | $62,500 |
| Real-Time Time-Series Anomaly Detection for Instruments | Invest | 62 | $202,500 |
| Information Sourcing | Maintain | 40 | — |
| Waters MassLynx | Maintain | 40 | — |
| FASTA | Maintain | 35 | $157,500 |
| Paleontological Statistics (PAST) | Maintain | 27 | — |
| VERBI MAXQDA | Maintain | 26 | — |
| Research Retrieval | Not rated | 25 | $37,500 |
| Instrument-Lab Data Integration Engineering | Invest | 23 | — |
| Deep-Learning Microscopy Image Segmentation | Invest | 20 | — |
| Untargeted Metabolomics Data Annotation | Monitor | 16 | — |
| LabArchives | Maintain | 15 | — |
| Human Performance Modeling | Maintain | 11 | — |
| Bayesian Experimental Inference | Invest | 9 | — |
| Promium Element DataSystem (LIMS) | Maintain | 8 | — |
| Cryo-EM Map Refinement and Model Building | Invest | 5 | — |
| Detector Simulation | Maintain | 4 | — |
| OriginPro | Maintain | 3 | — |
| Serial Femtosecond Crystallography Data Processing | Maintain | 3 | — |
| RSI interactive data language (IDL) | Monitor | 2 | — |
| SaTScan | Maintain | 1 | — |
| Scientific Software International BILOG-MG | Monitor | 1 | — |
| Scientific Software International PARSCALE | Monitor | 1 | — |
| Synergy Software KaleidaGraph | Maintain | 1 | — |
| Aquatic Plant Information Retrieval System (APIRS) | Monitor | — | — |
| Biometric Paleontology | Monitor | — | — |
| DAGRIS | Monitor | — | — |
| EMBOSS | Maintain | — | — |
| Edge AI Sensor Data Processing | Invest | — | — |
| Empirisoft DirectRT | Monitor | — | — |
| Empirisoft MediaLab | Monitor | — | — |
| Foundation Model Fine-Tuning for Scientific Data | Invest | — | — |
| Golden Helix ChemTree | Monitor | — | — |
| Google Books NGram Viewer | Monitor | — | — |
| Linear Expansion Simulation | Maintain | — | — |
| Logger data manager LDM | Not rated | — | — |
| LoggerPC | Monitor | — | — |
| Mangold Soundalyzer | Monitor | — | — |
| Mosflm | Maintain | — | — |
| NeTLIMS AutoFusion | Maintain | — | — |
| NetLims AutoLims | Maintain | — | — |
| PaleoTax | Maintain | — | — |
| Protein Structure Prediction Workflow | Invest | — | — |
| PsyScript | Monitor | — | — |
| QSR International NVivo | Maintain | — | — |
| Qaulis Research The Ethonograph | Monitor | — | — |
| Research Metadata Schema Design | Invest | — | — |
| Research Spectrum Survent (CATI) | Migrate | — | — |
| SACLANTCEN | Maintain | — | — |
| SequentiX TreeMe | Maintain | — | — |
| VASP Data Viewer | Maintain | — | — |
| Viking data editor | Monitor | — | — |
| Vogel Scientific Software Group (CALACO) | Monitor | — | — |
| Waters Millennium32 | Migrate | — | — |